BDBM50370476 Combivir::ZIDOVUDINE TRIPHOSPHATE
SMILES Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO[P@@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)O2)c(=O)[nH]c1=O
InChI Key InChIKey=GLWHPRRGGYLLRV-XLPZGREQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50370476
Affinity DataKi: 41nMAssay Description:Inhibition of HIV1 reverse transcriptase by steady state nucleotide incorporation assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataKd: 1.99E+3nMAssay Description:Binding affinity to wild type HIV1 LAI reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type in presence of 5 mM ATP by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of HIV1 pNL4-3 reverse transcriptase wild type pNL4-3 in presence of 5 mM ATP by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type LAI by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of HIV1 pNL4-3 reverse transcriptase wild type pNL4-3 by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.50E+4nMAssay Description:Binding affinity to HIV1 reverse transcriptase assessed as L-3'-azido-NTP incorporation in nascent DNAMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of HIV1 RT mediated DNA-dependent DNA synthesis initiation using RNA PPT primed substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of HIV1 RT mediated DNA-dependent DNA synthesis initiation using RNA/DNAM duplex primed substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase using T19-Cy5 labeled 23-mer DNA/T2-TAMRA labeled 63-mer DNA as primer/template assessed as inhibition of dN...More data for this Ligand-Target Pair